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Fig. 9 | Clinical Epigenetics

Fig. 9

From: Ultraviolet-B induces ERCC6 repression in lens epithelium cells of age-related nuclear cataract through coordinated DNA hypermethylation and histone deacetylation

Fig. 9

Knockdown of endogenous Sp1 decreased the mRNA expression and protein level of ERCC6 and Sp1 in 239T cells. a Detection of ERCC6 and Sp1 mRNA expression by qRT-PCR. Values represent mean ± SD. *P < 0.01. b Protein level of ERCC6 and Sp1 was examined by Western blot analysis. Results are presented as mean ± SD. c Relative ERCC6 protein level to GAPDH is presented as mean ± SD. *P < 0.01

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Clinical Epigenetics

ISSN: 1868-7083

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