Parameters | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
HR | 95Â % C.I. | P a | HR | 95Â % C.I. | P a | |
Gender (male vs. female) | 1.96 | 0.881–4.367 | 0.099 |  |  |  |
Age (≥60 years vs. <60 years) | 1.54 | 0.775–3.161 | 0.234 |  |  |  |
BMI (overweight vs. normal) | 2.23 | 0.966–5.164 | 0.060 |  |  |  |
Tumor location (distal vs. proximal) | 2.32 | 0.955–5.637 | 0.063 |  |  |  |
Pathology (mucinous vs. non-mucinous) | 1.71 | 0.409–7.166 | 0.462 |  |  |  |
Differentiation (high grade vs. low grade) | 1.41 | 0.428–4.619 | 0.575 |  |  |  |
T stage (T4 vs. T1, 2, 3) | 2.97 | 1.284–6.865 | 0.011 | 2.50 | 1.065–5.854 | 0.035 |
N stage (N2 vs. N0, 1) | 2.40 | 1.196–4.795 | 0.014 | 2.26 | 1.114–4.575 | 0.024 |
Microsatellite status (MSI-H vs. MSS + MSI-L) | 1.06 | 0.254–4.451 | 0.933 |  |  |  |
Performance status (PS ≥ 1 vs. PS 0) | 1.63 | 0.782–3.394 | 0.192 |  |  |  |
LINE-1 methylation (low vs. high) | 3.36 | 1.287–8.781 | 0.013 | 3.50 | 1.338–9.126 | 0.011 |