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Fig. 1 | Clinical Epigenetics

Fig. 1

From: TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus

Fig. 1

TREM2 mRNA expression is increased in human hippocampus in Alzheimer’s disease (AD). a The graph shows a significant 3.4-fold increase in TREM2 mRNA levels in AD hippocampal samples compared to control hippocampal samples. b TREM2 mRNA expression increases across AD stages, as shown when TREM2 mRNA expression levels are sorted by Braak & Braak stages. Bars represent percentage of TREM2 mRNA expression relative to the geometric mean of HPRT and ACTB housekeeping genes expression. Vertical lines represent the standard error of the mean.*p value <0.05; **p value <0.005; ***p value <0.0005

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