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Table 4 Change of mirtronic miRNA expression levels in response to the overexpression of splicing factors

From: Splicing-dependent expression of microRNAs of mirtron origin in human digestive and excretory system cancer cells

Overexpressed splicing factor

Change of mirtronic miRNA expression levels, folds (p value)

miR-1226

miR-1227

miR-1229

SRSF1 (3.2 ± 0.6-fold)

1.5 ± 0.6 (p = 0.23)

−1.1 ± 0.4 (p = 0.47)

1.7 ± 0.4a (p = 0.05)

SRSF2 (1.6 ± 0.5-fold)

1.5 ± 0.8 (p = 0.15)

1.9 ± 0.7a (p = 0.008)

1.4 ± 0.3a (p = 0.008)

  1. A significance level of 0.05 was applied as a cutoff value
  2. aStatistically significant results
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Clinical Epigenetics

ISSN: 1868-7083

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