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Table 2 Differential expression of mirtronic miRNAs in pancreas, kidney, colon, and stomach cancer cell lines

From: Splicing-dependent expression of microRNAs of mirtron origin in human digestive and excretory system cancer cells

Organ

Cell line

miRNAs of mirtron origin

Non-mirtronic miRNA

miR-1226-3p

miR-1227-3p

miR-1229-3p

miR-1236-3p

miR-1238-3p

Pancreas

PANC-1

−2.8 ± 1.8a

−1.7 ± 0.3a

−2.8 ± 0.9a

−1.4 ± 0.2

−1.2 ± 0.6

SU.86.86

−3.4 ± 0.9a

−2.1 ± 0.4a

+5.0 ± 2.7b

+3.8 ± 0.6b

+2.8 ± 0.9b

T3M4

−2.2 ± 0.4a

−2.6 ± 0.4a

+2.1 ± 0.3b

+1.9 ± 0.4b

+1.3 ± 0.2

Kidney

CaKi-1

−4.9 ± 2.1a

−3.9 ± 1.6a

−1.2 ± 0.6

+1.3 ± 0.7

1.0 ± 0.8

786-O

−4.6 ± 2.2a

−2.6 ± 0.7a

−1.1 ± 0.2

−1.8 ± 0.2a

−1.1 ± 0.2

Colon

HCT116

−2.7 ± 0.8a

−2.2 ± 0.8a

−1.3 ± 0.2

1.0 ± 0.7

−4.2 ± 0.3a

Stomach

KATOIII

−1.9 ± 0.3a

−2.0 ± 0.4a

+2.7 ± 0.3b

−2.2 ± 0.3a

+1.3 ± 0.0

  1. Fold changes higher than 1.5 were statistically significant (p < 0.05)
  2. aReduced expression compared to the non-cancerous HEK 293A cells
  3. bEnhanced expression