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Table 6 Univariate and multivariate Cox analyses on overall survival of cancer patients

From: Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites

Ā 

Univariate Cox analysis

Multivariate Cox analysis

Ā 

Hazard ratio [95Ā % CI]

p value

Hazard ratio [95Ā % CI]

p value

Cytology (negative as reference)

Ā Ā Ā Ā 

Positive

1.37 [0.78ā€“2.41]

0.275

Ā Ā 

Suspicious

0.82 [0.34ā€“1.96]

0.657

Ā Ā 

Gender (male as reference)

0.69 [0.41ā€“1.16]

0.217

Ā Ā 

Age (discrete variable)

1.03 [1.00ā€“1.06]

0.022

1.03 [1.00ā€“1.06]

0.022

Cell-free SHOX2ā€‰+ā€‰SEPT9

Ā 

0.161*

Ā Ā 

Positive (negative as reference)

1.21 [0.64ā€“2.31]

0.557

Ā Ā 

No DNA (negative as reference)

0.67 [0.35ā€“1.28]

0.222

Ā Ā 

No DNA (positive as reference)

0.55 [0.30ā€“1.03]

0.060

Ā Ā 
  1. Results of cfDNA methylation analyses (nā€‰=ā€‰81). p values indicated by ā€œ*ā€ refer to overall effect of the categorical variables irrespective of the reference levels