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Table 6 Univariate and multivariate Cox analyses on overall survival of cancer patients

From: Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites

  Univariate Cox analysis Multivariate Cox analysis
  Hazard ratio [95 % CI] p value Hazard ratio [95 % CI] p value
Cytology (negative as reference)     
Positive 1.37 [0.78–2.41] 0.275   
Suspicious 0.82 [0.34–1.96] 0.657   
Gender (male as reference) 0.69 [0.41–1.16] 0.217   
Age (discrete variable) 1.03 [1.00–1.06] 0.022 1.03 [1.00–1.06] 0.022
Cell-free SHOX2 + SEPT9   0.161*   
Positive (negative as reference) 1.21 [0.64–2.31] 0.557   
No DNA (negative as reference) 0.67 [0.35–1.28] 0.222   
No DNA (positive as reference) 0.55 [0.30–1.03] 0.060   
  1. Results of cfDNA methylation analyses (n = 81). p values indicated by “*” refer to overall effect of the categorical variables irrespective of the reference levels