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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites

Fig. 1

DNA methylation of SHOX2 and SEPT9 in ascitic samples from cancer and non-cancer patients. Comparison of SHOX2 and SEPT9 methylation of ascitic DNA from cancer patients and patients with exclusively non-malignant diseases determined by quantitative real-time PCR. Methylation cutoffs were introduced for SHOX2 and SEPT9 to dichotomize patient samples as SHOX2 or SEPT9 positive (above the cutoff) or negative (below the cutoff), respectively. The indicated p values refer to the Mann-Whitney U tests. a DNA methylation analysis of the cellular fractions of ascites samples (n = 283). b Methylation results of cell-free ascitic DNA (n = 162)

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