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Table 2 Number of associations between DNA methylation and hormone receptor-positive breast cancer in the BCCC dataset

From: DNA methylation and hormone receptor status in breast cancer

Analysis Number of coefficientsa No. of positive associations No. of inverse associations % positiveb 95 % CI Ratioc 95 % CI
Training dataset (N = 807 genes)        
All associations 806 548 258 68 (66, 72) 2.2 (1.9, 2.6)
Associations with P value ≤0.20 180 146 34 81 (75, 86) 4.3 (3.0, 6.4)
Associations with P value ≤0.05 46 38 8 83 (70, 93) 4.8 (2.4, 12.7)
  1. aNumber of logistic regression coefficients involved in each analysis
  2. bPercentage of coefficients that represent a positive association between methylation and hormone receptor-positive breast cancer.
  3. cRatio of the number of positive divided by the number of negative associations