Table 1 Main clinico-pathologic characteristics of CRCs
From: Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer
| Â | LS-MSI | S-MSI | S-MSS | EO-MSS |
|---|---|---|---|---|
| Â | No. of tumors/totala (%) | |||
Age | Â | Â | Â | Â |
- Mean, years | 47.1 | 70.5 | 69.5 | 35.4 |
- Range, years | 30–78 | 41–88 | 41–91 | 24–40 |
Gender | Â | Â | Â | Â |
- Female | 33/71 (47) | 10/28 (36) | 41/94 (44) | 7/23 (30) |
- Male | 38/71 (53) | 18/28 (64) | 53/94 (56) | 16/23 (70) |
Site | Â | Â | Â | Â |
- Proximal colon | 36/52 (69) | 26/28 (93) | 27/98 (28) | 3/23 (13) |
- Distal colon | 16/52 (31) | 2/28 (7) | 71/98 (72) | 20/23 (87) |
Histological type | Â | Â | Â | Â |
- Mucinous | 21/67 (31) | 18/28 (64) | 7/98 (7) | 3/23 (13) |
- Medullary | 8/67 (12) | 8/28 (29) | 0/98 (0) | 0/23 (0) |
- Signet ring cell | 8/67 (12) | 4/28 (15) | 4/98 (4) | 0/23 (0) |
Tumor grade | Â | Â | Â | Â |
- G1, G2 | 30/62 (48) | 13/28 (46) | 83/98 (85) | 20/23 (87) |
- G3 | 32/62 (52) | 15/28 (54) | 15/98 (15) | 3/23 (13) |
TNM stage | Â | Â | Â | Â |
- I–II | 48/67 (72) | 18/25 (72) | 38/93 (41) | 8/22 (36) |
- III–IV | 19/67 (28) | 7/25 (28) | 55/93 (59) | 14/22 (64) |
Follow-up | Â | Â | Â | Â |
- Alive | 39/53 (74) | 22/26 (85) | 50/94 (53) | 15/23 (68) |
- Died of disease | 14/53 (26) | 4/26 (15) | 44/94 (47) | 7/23 (32) |