Table 5 Comparison of sensitivity and specificity of previous and modified MMSP markers on DNAs from NPC and control samples from Morocco, Italy, and China using at least any one viral or cellular marker (irrespective of EBNA1 status)
Origin | DNA source | Previous panel of markers | Modified panel of markers | ||
|---|---|---|---|---|---|
| Â | Â | Sensitivity | Specificity | Sensitivity | Specificity |
Morocco | Tumor | 84Â % (37/44) | 67Â % (12/18) | 89Â % (39/44) | 94Â % (17/18) |
Italy | Tumor | Â | Â | 93Â % (14/15) | NA |
Serum | Â | Â | 91Â % (10/11) | 50Â % (4/8) | |
China | Tumor | Â | Â | 100Â % (5/5) | 50Â % (1/2) |
Serum | Â | Â | 80Â % (4/5) | NA | |
Total | Tumor | 84Â % (37/44) | 67Â % (12/18) | 91Â % (58/64) | 90Â % (18/20) |
Serum | Â | Â | 88Â % (14/16) | 50Â % (4/8) | |