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Table 1 New Hampshire Mammography Network patient and DCIS characteristics

From: DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer

 

All DCIS

No invasive BRCA

Invasive BRCA

 

Covariate

n = 40

n = 27 (67.5 %)

n = 13 (32.5 %)

P value

Age (years)

    

 Range

37–78

37–78

38–76

 

 Median

59

63

52

 

 Mean (sd)

58.2 (12.8)

59.1 (13.0)

56.5 (12.9)

0.55

Follow-up time (years)

    

 Median

7.01

8.55

2.94

 

 Range

0.94–15.49

2.85–15.49

0.94–10.33

1.60E-04

Grade

    

 Low/Intermediate (%)

28 (70.0)

17 (63.0)

11 (84.6)

 

 High

12 (30.0)

10 (37.0)

2 (15.4)

0.27

Tumor size (cm)

    

 Median

1.20

1.4

1.15

 

 Range

0.15–7.5

0.2–7.5

0.15–2.1

 

 Missing

8

5

3

0.64

Family history of breast cancer

    

 No (%)

25 (62.5)

17 (63.0)

8 (61.5)

 

 Yes

15 (37.5)

10 (37.0)

5 (38.5)

1.0

Menopausal status

    

 Pre-menopausal (%)

15 (37.5)

9 (33.3)

6 (46.2)

 

 Post-menopausal

25 (62.5)

18 (66.7)

7 (53.8)

0.59

  1. T-tests or Wilcoxon tests were applied for numeric variables, while Fisher’s exact test was used for count data
  2. P value represents results from univariate tests between study groups