Table 1 Differentially expressed genes in A2058 cells used by vitamin C treatment
From: Epigenetic reprogramming of melanoma cells by vitamin C treatment
No | Symbol | Gene | RNA-seq (DESeq) | qRT-PCR | ||
|---|---|---|---|---|---|---|
| Â | Fold | P value | Fold | P value | ||
1 | ARGHAP30 | Rho GTPase activating protein 30 | 15.2 | 4.73 × 10−21 | 10.3 | 2.2 × 10−5 |
2 | TRIM63 | Tripartite motif containing 63, E3 ubiquitin-protein ligase | 5.3 | 2.15 × 10−05 | 4.3 | 2.2 × 10−5 |
3 | PTPN7 | Protein tyrosine phostaphatase, non-receptor type 7 | 3.8 | 0.01 | 2.6 | 8 × 10 |
4 | SOCS3 | Suppressor of cytokine signaling 3 | 1.9 | 1 × 10−4 | 2 | 9 × 10−3 |
5 | FAP | Fibroblast activation protein, alpha | 1.7 | 3.43 × 10−21 | 1.6 | 0.01 |
6 | GPRIN3 | GPRIN family member 3 | 1.7 | 5 × 10−5 | 2 | 3 × 10−4 |
7 | TIMP3 | TIMP metallopeptidase inhibitor 3 | 1.6 | 5 × 10−5 | 1.5 | 0.01 |
8 | MAGEA4 | Melanoma antigen family A | 1.6 | 5 × 10−5 | 1.8 | 1 × 10−4 |
9 | SERPINE2 | Serpin, peptidase inhibitaor clade E, member 2 | 0.67 | 2.5 × 10−4 | 0.79 | 0.01 |
10 | SLITRK2 | SLIT and NTRK-like family member 2) | 0.49 | 1 × 10−4 | 0.66 | 2 × 10−3 |