Bars representing the mean ± standard error for miR-221, miR-222, and miR-155. Bars representing the mean ± standard error for miR-221, miR-222, and miR-155 in differentiated adipocytes and their SN at the baseline and upon MCM-conditioned inflammation (striped bars) and in human AT before (striped bars)-after massive weight loss. The geometric average of all analyzed miRNAs was used as normalizing factor in cells and the SNs, respectively. RNU6b was used as reference miRNA in human adipose tissue. Bottom tables provide normalized values as mean ± standard deviation (minimum-maximum). *P < 0.05, **P < 0.01, and #
P < 0.0001 (Student’s or paired t-test) for comparisons treatment vs. control, pre- vs. post-weight loss.