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Table 3 Hypomethylated and transcriptionally induced genes ( n = 30) in HCC as compared to cancer-free tissue

From: DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma

Cell communication (6) a
Gene Name P value Coefficient
ASAP1 0.015 1.3
CD34 0.03 1.5
GLDN 0.006 1.2
MYBPC1 0.026 1.4
RIMS2 0.03 2.2
TRIM55 0.0002 2.8
Immune response (8) a
Gene Name P value Coefficient
CD200 0.038 2.1
CTLA4 0.018 2.2
CXCL10 0.048 1.6
DCSTAMP 0.03 1.1
LRRC69 0.015 1.0
NOX4 0.018 1.6
SSX6 0.03 3.2
SSX8 0.019 3.4
Transport (2) a
Gene Name P value Coefficient
KIF4A 0.006 2.2
SLC7A11 0.006 2.6
Metabolic and cellular process (3) a   
Gene Name P value Coefficient
DTNA 0.044 2.0
HIST1H4F 0.022 1.7
SPINK1 0.0004 4.2
Cell growth, cell cycle and apoptosis (4) a
Gene Name P value Coefficient
ESM1 0.002 2.0
GINS4 0.013 1.4
LTA 0.009 1.0
MAP2 0.009 1.0
Miscellaneous (7) a
Gene Name P value Coefficient
C15orf42 0.002 1.9
FBXO32 0.003 2.1
KIAA1688 0.001 1.6
POTEA 0.009 1.7
POTEC 0.018 1.5
VCX2 0.017 2.0
VCX3A 0.012 2.4
  1. aNumber of genes hypermethylated and transcriptionally repressed. Coefficient and P value refer to gene expression data.