Figure 5
From: The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth
IGF1 transcripts. (A) P1-driven, P2-driven, and total IGF1 transcripts in the PBMC from 49/216 children. (B) Correlation between class I P1-driven transcripts and class II P2-driven transcripts Y = 0.55X − 2.96 (R = 0.66, P = 1.4 × 10−7). (C) Inverse correlation between CG-137 methylation and P2-driven transcripts Y = −0.09X − 2.3 (R = −0.67, P = 7 × 10−8). (D) Inverse correlation between CG-137 methylation and P1-driven transcripts Y = −0.06X − 2.93 (R = −0.67, P = 2.7 × 10−3). (E) Inverse correlation between CG-137 methylation and all IGF1 transcripts Y = −0.09X − 1.6 (R = −0.65, P = 2.8 × 10−7).