Table 5 Clinical, comorbidity and demographic factors for normal human liver cohort
PATIENT | Gender | Indication resection | Pre-op chemo | Regimen | Comorbidity | Diabetes | Medication | Background liver histology |
|---|---|---|---|---|---|---|---|---|
1 | Female | Intrahepatic cholangiocarcinoma | No | Nil | No | Nil | Bridging fibrosis and chronic cholestasis | |
2 | Male | Colorectal mets | No | Nil | No | Nil | Mild inflammation portal tracts | |
3 | Male | Extrahepatic cholangiocarcinoma | No | Nil | No | Nil | Mild chronic inflammation portal tracts and minimal steatosis | |
4 | Female | Colorectal mets | Yes | FOLFIRI and Bevacizumab | Ischaemic heart disease; hypertension; thoracic outlet syndrome | No | Aspirin; bendroflazide; fluoxetine; isosorbide mononitrate; lansoprazole; simvastatin | Normal |
5 | Female | Colorectal mets | No | Cleft palate; malnutrition | No | Aspirin; ferrous fumarate | Normal | |
6 | Female | Colorectal mets | Yes | FOLFOX and Cetuximab | Nil | No | Nil | Mild to moderate macrovesicular steatosis; degree of nodular regenerative hyperplasia |
7 | Male | Colorectal mets | No | Anxiety | No | Amitriptyline; propanolol; tamsulosin, loperamide | Macrovesicular steatosis | |
8 | Male | Colorectal mets | No | FOLFIRI and Bevacizumab | Hypertension | No | Amlodipine; ramipril | Mild steatosis only |
9 | Female | Colorectal mets | No | Nil | No | Omeprazole; temazepam | Minimal macrovesicular steatosis | |
10 | Female | Colorectal mets | No | Capecitabine and Bevacizumab | Hypertension; hiatus hernia | No | Amlodipine; lansoprazole; pyridoxine; ramipril | Unremarkable |
11 | Female | Colorectal mets | No | Nil | No | Nil | Unremarkable | |
12 | Male | Colorectal mets | No | Nil | No | Nil | Normal | |
13 | Male | Colorectal mets | No | Nil | No | Nil | Normal | |
14 | Male | HCC | No | Hypertension | No | Atenolol; candesartan; lercanidipine; simvastatin | Moderate macrovesicular steatosis - no fibrosis or steatohepatitis | |
15 | Male | HCC | No | Colorectal cancer | No | Aspirin | Minimal macrovesicular steatosis | |
16 | Male | Colorectal mets | No | Ischaemic heart disease | Ramipril; simvastatin; bisoprolol; aspirin | Mild macrovesicular steatosis and chronic inflammation of portal tracts; no steatohepatitis or fibrosis | ||
17 | Male | HCC | No | Breast cancer; Parkinson’s disease; coeliac disease; asthma | Betahistine; Calci-chew; Co-beneldopa; Co-careldopa; ferrous fumarate; fluoxetine; seretide; ipratropium; stalevo; omeprazole; oxytetracyline; ropinirole; salbutamol | Mild sinusoidal dilatation otherwise normal |