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Table 1 Clinical characteristics of child bearing group (female 19 to 39 years) from NDNS and pregnant women from Saudi population

From: Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes

  NDNS Saudi cohort
Total B 12 (ng/L) Total Maternal B 12 (ng/L)
n= 315 >190 ( n= 278) ≤190 ( n= 37) n= 152 >190 ( n= 84) ≤190 ( n= 68)
Age (years) 31.2 ± 0.32 31.7 ± 0.34 30.5 ± 0.94 28.6 ± 0.43 28.5 ± 0.59 28.5 ± 0.62
BMI (kg/m2) 25.3 ± 0.29 25.2 ± 0.30 26.3 ± 1.0 26.75 ± 0.43 26.0 ± 0.55 27.8 ± 0.66*
WHR 0.77 ± 0.003 0.77 ± 0.003 0.79 ± 0.01 - - -
Total-C (mmol/L) 4.84 ± 0.06 4.79 ± 0.06 5.20 ± 0.21* 5.98 ± 0.09 5.80 ± 0.12 6.20 ± 0.15*
LDL-C (mmol/L) 3.58 ± 0.06 3.52 ± 0.06 4.01 ± 0.21** 3.02 ± 0.14 2.99 ± 0.18 3.14 ± 0.21
HDL-C (mmol/L) 1.26 ± 0.02 1.27 ± 0.02 1.19 ± 0.06 1.25 ± 0.03 1.25 ± 0.04 1.24 ± 0.04
Total-C:HDL ratio 4.11 ± 0.08 4.03 ± 0.08 4.70 ± 0.26** 5.11 ± 0.14 4.99 ± 0.18 5.29 ± 0.22
TG (mmol/L) - - - 1.77 ± 0.05 1.64 ± 0.06 1.93 ± 0.07**
Folate (μg/L) 9.24 ± 0.21 9.35 ± 0.23 8.46 ± 0.51 10.4 ± 0.34 10.4 ± 0.49 10.5 ± 0.46
Homocysteine (μmol/L) 9.98 ± 0.21 9.78 ± 0.21 11.53 ± 0.65** 4.74 ± 0.13 4.45 ± 0.17 5.11 ± 0.21*
  1. P value compared to B12 (>190 ng/L) group; *P < 0.05; **P < 0.01. Continuous variables are mean ± SEM.