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Table 7 The effects of SNP, DNA methylation, and their interaction effects in selected models ( IL4 )

From: The interplay of DNA methylation over time with Th2 pathway genetic variants on asthma risk and temporal asthma transition

Model Model frequency# Parameter   Effects at age 10 (n = 34); Log-OR (P value) Effects at age 18 (n = 233); Log-OR (P value)$
6 532 cg23943829   −2.17 (1.00) −3.60 (0.009)
rs2070874 AG −22.16 (1.00) −4.97 (0.4)
GG Ref. Ref.
cg23943829* rs2070874 AG 2.17 (1.00) 2.61 (0.4)
GG Ref. Ref.
7 669 cg23943829   −1.60 (0.64) −4.47 (0.003)
rs2243250 AG −21.18 (1.00) −6.75 (0.2)
GG Ref. Ref.
cg23943829* rs2243250 AG 1.60 (1.00) 3.84 (0.1)
GG Ref. Ref.
  1. #The frequency is based on 1,000 bootstrap samples.
  2. $P values significant at the 0.01 level at age 18 are in bold font.