Table 1 Characteristics of subjects with available methylation data compared to the female participants of the total cohort
Total female participants, n(%) | Female participants with DNA-M data, n(%) | P value | |
|---|---|---|---|
Factors | n = 660 | n = 245 | |
Maternal smoking during pregnancy | |||
Yes | 159 (24.1) | 47 (19.2) | |
No | 498 (75.5) | 197 (80.4) | 0.29 |
Missing | 7 | 1 (0.41) | |
Maternal history of asthma | |||
Yes | 67 (10.2) | 30 (12.2) | |
No | 588 (89.1) | 213 (86.9) | 0.66 |
Missing | 5 (0.8) | 2 (0.82) | |
Asthma at 18 years | |||
Yes | 128 (19.4) | 35 (14.3) | |
No | 531 (80.5) | 210 (85.7) | 0.17 |
Missing | 1 (0.2) | 0 | |
Oral contraceptive use at 18 years | |||
Yes | 293 (44.4) | 117 (47.8) | |
No | 335 (50.7) | 126 (51.4) | 0.02 |
Missing | 32 (4.9) | 2 (0.8) | |
Smoking at 18 years | |||
Yes | 192 (29.1) | 63 (25.7) | |
No | 455 (68.9) | 181(73.9) | 0.13 |
Missing | 13 (2.0) | 1 (0.4) | |
Socioeconomic status | |||
High | 49 (7.4) | 22 (9.0) | |
Medium | 479 (72.6) | 182 (74.3) | 0.69 |
Low | 94 (14.2) | 37 (15.1) | |
Missing | 38 (5.8) | 4 (5.8) | |
n (Median; 5%, 95%) | n (Median; 5%, 95%) | ||
Body mass index at 10 years (kg/m 2 ) | 527 (17.9;14.8, 25.2) | 223 (17.9;15.04, 25.3) | 0.92 |
Missing | 223 | 22 | |
Body mass index at 18 years (kg/m 2 ) | 499 (22.2;18.2, 32) | 240 (22.9;19.05, 32.93) | 0.56 |
Missing | 251 | 5 | |
Age at menarche | 631 (13.0;11.0,15.0) | 233 (13.0;10.0, 15.0) | 0.32 |
Missing | 119 | 12 |