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Table 1 Characteristics of subjects with available methylation data compared to the female participants of the total cohort

From: Oral contraceptives modify the effect of GATA3 polymorphisms on the risk of asthma at the age of 18 years via DNA methylation

  Total female participants, n(%) Female participants with DNA-M data, n(%) P value
Factors n = 660 n = 245  
Maternal smoking during pregnancy    
Yes 159 (24.1) 47 (19.2)  
No 498 (75.5) 197 (80.4) 0.29
Missing 7 1 (0.41)  
Maternal history of asthma    
Yes 67 (10.2) 30 (12.2)  
No 588 (89.1) 213 (86.9) 0.66
Missing 5 (0.8) 2 (0.82)  
Asthma at 18 years    
Yes 128 (19.4) 35 (14.3)  
No 531 (80.5) 210 (85.7) 0.17
Missing 1 (0.2) 0  
Oral contraceptive use at 18 years    
Yes 293 (44.4) 117 (47.8)  
No 335 (50.7) 126 (51.4) 0.02
Missing 32 (4.9) 2 (0.8)  
Smoking at 18 years    
Yes 192 (29.1) 63 (25.7)  
No 455 (68.9) 181(73.9) 0.13
Missing 13 (2.0) 1 (0.4)  
Socioeconomic status    
High 49 (7.4) 22 (9.0)  
Medium 479 (72.6) 182 (74.3) 0.69
Low 94 (14.2) 37 (15.1)  
Missing 38 (5.8) 4 (5.8)  
  n (Median; 5%, 95%) n (Median; 5%, 95%)  
Body mass index at 10 years (kg/m 2 ) 527 (17.9;14.8, 25.2) 223 (17.9;15.04, 25.3) 0.92
Missing 223 22  
Body mass index at 18 years (kg/m 2 ) 499 (22.2;18.2, 32) 240 (22.9;19.05, 32.93) 0.56
Missing 251 5  
Age at menarche 631 (13.0;11.0,15.0) 233 (13.0;10.0, 15.0) 0.32
Missing 119 12