Table 1 Association of clinical and laboratory parameters with PTEN methylation status

Heavy chain

0.8

IgG

40

6

IgA

10

1

IgM

1

0

Light chain

0.04

Kappa

25

7

Lambda

16

0

Stage

I

14

4

0.3

II

10

1

III

25

2

Age (mean in years)

67.6 ± 13.0

69 ± 10.1

0.7

White blood cells (mean n°x10^3/mcL)

6.58 ± 2.2

6.0 ± 2.9

0.5

Hemoglobin (mean in g/dL)

10.2 ± 2.1

11.2 ± 1.9

0.2

Platelets (mean n°x10^3/mcL)

235 ± 95

210 ± 65

0.5

Lactate dehydrogenase (mean in U/L)

379 ± 186

200 ± 40

0.01

β2-microglobuline (mg/dL)

5.3 ± 4.5

5.3 ± 5.4

0.9

Albumin (mean in g/dL)

3.6 ± 0.7

3.9 ± 0.8

0.3

Serum creatinine (mean in mg/dL)

2.0 ± 2.35

1.0 ± 0.6

0.2

Calcium (mean in mg/dL)

6.0 ± 2.5

7.1 ± 2.5

0.3

Protein (mean in g/L)

8.5 ± 1.8

8.8 ± 1

0.66

Plasma cells (mean in %)

52 ± 31

58 ± 24

0.6

Cytogenetic risk

0.68

Standard

31

5

Intermediate

15

1

High

5

1