Developmental genes targeted for epigenetic variation between twin-twin transfusion syndrome children

Clinical Epigenetics

Table 2 Number of loci with large differences in methylation between donors and recipients, and their relationship to surgery age and current age

Sample type	Donor ID	Recipient ID	Total number of loci with methylation difference >0.2 or <−0.2	Gestational age at laser surgery (weeks)	Current age when sampled (years)
Saliva	614	651	296	15.86	0.42
Saliva	663	576	551	20.86	3
Saliva	556	604	540	18.14	5
Blood	614	651	24	15.86	0.42
Blood	556	604	6	18.14	5

Pearson correlation between age of fetal surgery and number of loci with a large difference in saliva is 0.86 (P <0.3). Pearson correlation between the age when the sample was obtained and the number of loci with large difference in saliva is 0.88 (P <0.3).

ISSN: 1868-7083