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Table 1 The frequencies of relapsed and secondary acute myeloid leukemia (AML), signs of differentiation (FAB subclasses, CD34 expression) and genetic abnormalities among unselected AML patients unfit for intensive therapy

From: The combination of valproic acid, all-trans retinoic acid and low-dose cytarabine as disease-stabilizing treatment in acute myeloid leukemia

FAB classification

 

  M0/M1

0.41

  M2

0.23

  M4/M5

0.36

Expression of CD34 (> 20% positive cells)

0.70

Cytogenetic abnormalities

 

  Normal

0.50

  Good

0.00

  Intermediate

0.20

  Adverse

0.30

Flt3- internal tandem duplication

0.40

NPM-1 mutation

0.35