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Table 3 Adjusted log-linear regression model of the interaction of genetic variants and DNA methylation of the IL4R gene on asthma at age 18 years

From: The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

Parameter   Estimate 95% CI P value
Intercept   19.59 −12.78 51.97 0.25
cg09791102   −26.97 −63.62 9.67 0.14
rs3024685 CC −102.45 −158.51 −46.40 0.0003
CT −38.48 −80.71 3.75 0.07
TT Reference    
cg09791102* rs3024685 CC 115.54 53.18 177.91 0.0003
CT 43.90 −3.45 91.27 0.06
TT Reference    
rs3024622 CC −1.24 −3.45 0.95 0.26
CG −0.14 −1.00 0.72 0.74
GG Reference    
rs12102586 TT 2.41 0.29 4.53 0.02
CT 0.65 −0.24 1.55 0.15
CC Reference    
rs16976728 TT −0.53 −2.03 0.95 0.48
CT 0.16 −0.78 1.11 0.72
CC Reference    
Maternal smoking during pregnancy 0.43 −0.40 1.26 0.31
Maternal history of asthma 0.53 −0.41 1.49 0.26
Body mass index at age 18 years (kg/m2) 0.05 −0.009 0.12 0.09
Breastfeeding duration (weeks) 0.02 −0.004 0.04 0.11