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Table 3 Univariate regression of head circumference on IGF/H19 ICR

From: DNA methylation of the IGF2/H19 imprinting control region and adiposity distribution in young adults

 

Coefficient

P-value

95% CI

CpG1

−0.08

0.12

−0.17 to 0.02

CpG5-8

−0.05

0.27

−0.14 to 0.04

CpG11-12

−0.9

0.089

−0.19 to 0.01

CpG13-14

−0.12

0.006

−0.21 to −0.04

CpG21-22

−0.07

0.11

−0.16 to 0.02

CpG23

0.04

0.38

−0.05 to 0.13

Principal component 1

−0.07

0.14

−0.16 to 0.02

Principal component 2

0.07

0.17

−0.03 to 0.18

  1. Head circumference is associated with each of the six CpG units and on principal components 1 and 2 of DNA methylation. Within subject correlation across time between 1 and 10 years of age was accounted for using a sandwich estimator (vce option in STATA).