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Table 2 Concomitant JAK2 mutation and SFRP-2 hypermethylation in MPN patients

From: Epigenetic dysregulation of secreted frizzled-related proteins in myeloproliferative neoplasms complements the JAK2V617F-mutation

 

CML (n= 10)

PV (n= 10)

ET (n= 10)

MF (n= 27)

SFRP-2

U

M

U

M

U

M

U

M

JAK2, wt

10

0

1

1

4

1

12

1

JAK2V617F

0

0

6

2

2

3

8

6

  1. CML, chronic myeloid leukemia; ET, essential thrombocythemia; M, methylated; MF, myelofibrosis; PV, polycythemiavera; U, unmethylated; wt = negative for JAK2V617F.