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Table 2 Concomitant JAK2 mutation and SFRP-2 hypermethylation in MPN patients

From: Epigenetic dysregulation of secreted frizzled-related proteins in myeloproliferative neoplasms complements the JAK2V617F-mutation

  CML (n= 10) PV (n= 10) ET (n= 10) MF (n= 27)
SFRP-2 U M U M U M U M
JAK2, wt 10 0 1 1 4 1 12 1
JAK2V617F 0 0 6 2 2 3 8 6
  1. CML, chronic myeloid leukemia; ET, essential thrombocythemia; M, methylated; MF, myelofibrosis; PV, polycythemiavera; U, unmethylated; wt = negative for JAK2V617F.