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  1. Chronological age is a prominent risk factor for many types of cancers including colorectal cancer (CRC). Yet, the risk of CRC varies substantially between individuals, even within the same age group, which ma...

    Authors: Ting Wang, Sean K. Maden, Georg E. Luebeck, Christopher I. Li, Polly A. Newcomb, Cornelia M. Ulrich, Ji-Hoon E. Joo, Daniel D. Buchanan, Roger L. Milne, Melissa C. Southey, Kelly T. Carter, Amber R. Willbanks, Yanxin Luo, Ming Yu and William M. Grady

    Citation: Clinical Epigenetics 2020 12:5

    Content type: Research

    Published on:

  2. Poor-responsiveness of tumors to radiotherapy is a major clinical problem. Owing to the dynamic nature of the epigenome, the identification and targeting of potential epigenetic modifiers may be helpful to cur...

    Authors: Asmita Sharda, Mudasir Rashid, Sanket Girish Shah, Ajit Kumar Sharma, Saurav Raj Singh, Poonam Gera, Murali Krishna Chilkapati and Sanjay Gupta

    Citation: Clinical Epigenetics 2020 12:4

    Content type: Research

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  3. Non-alcoholic fatty liver disease is the most common chronic liver disease in children in western countries. Adverse early-life exposures are associated with higher liver fat percentages in children. Different...

    Authors: Madelon L. Geurtsen, Vincent W. V. Jaddoe, Lucas A. Salas, Susana Santos and Janine F. Felix

    Citation: Clinical Epigenetics 2019 12:3

    Content type: Research

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  4. While circulating nucleosome levels are high in obese mouse models, it is unknown where these nucleosomes originate from and whether they are a marker of cardio-metabolic health in humans. Here, we aimed to de...

    Authors: Oriana Lo Re, Andrea Maugeri, Jana Hruskova, Juraj Jakubik, Jan Kucera, Julie Bienertova-Vasku, Jude A. Oben, Lukas Kubala, Adela Dvorakova, Milan Ciz and Manlio Vinciguerra

    Citation: Clinical Epigenetics 2019 12:2

    Content type: Research

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  5. Crohn’s disease is a chronic inflammatory disorder of the gastrointestinal tract associated with abdominal pain and diarrhea. Pain caused by Crohn’s disease likely involves neurogenic inflammation which seems ...

    Authors: Sara Gombert, Mathias Rhein, Andreas Winterpacht, Tino Münster, Thomas Hillemacher, Andreas Leffler and Helge Frieling

    Citation: Clinical Epigenetics 2019 12:1

    Content type: Research

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  6. Epigenetic regulations play pivotal roles in tumorigenesis and cancer development. Disruptor of telomeric silencing-1-like (DOT1L), also known as KMT4, is the only identified histone methyltransferase that cat...

    Authors: Liqun Yang, Qian Lei, Lin Li, Jie Yang, Zhen Dong and Hongjuan Cui

    Citation: Clinical Epigenetics 2019 11:199

    Content type: Research

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  7. Metabolic side effects induced by psychotropic drugs represent a major health issue in psychiatry. CREB-regulated transcription coactivator 1 (CRTC1) gene plays a major role in the regulation of energy homeostasi...

    Authors: Aurélie Delacrétaz, Anaïs Glatard, Céline Dubath, Mehdi Gholam-Rezaee, Jose Vicente Sanchez-Mut, Johannes Gräff, Armin von Gunten, Philippe Conus and Chin B. Eap

    Citation: Clinical Epigenetics 2019 11:198

    Content type: Research

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  8. In vitro follicle culture (IFC), as applied in the mouse system, allows the growth and maturation of a large number of immature preantral follicles to become mature and competent oocytes. In the human oncofert...

    Authors: Maria Desemparats Saenz-de-Juano, Elena Ivanova, Katy Billooye, Anamaria-Cristina Herta, Johan Smitz, Gavin Kelsey and Ellen Anckaert

    Citation: Clinical Epigenetics 2019 11:197

    Content type: Research

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    The Correction to this article has been published in Clinical Epigenetics 2020 12:18

  9. Aberrations in DNA methylation are widespread in colon cancer (CC). Understanding origin and progression of DNA methylation aberrations is essential to develop effective preventive and therapeutic strategies. ...

    Authors: Faiza Noreen, Taya Küng, Luigi Tornillo, Hannah Parker, Miguel Silva, Stefan Weis, Giancarlo Marra, Roland Rad, Kaspar Truninger and Primo Schär

    Citation: Clinical Epigenetics 2019 11:196

    Content type: Research

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  10. Trisomy 21 (T21) is associated with intellectual disability that ranges from mild to profound with an average intellectual quotient of around 50. Furthermore, T21 patients have a high risk of developing Alzhei...

    Authors: Larissa Haertle, Tobias Müller, Roy Lardenoije, Anna Maierhofer, Marcus Dittrich, Renzo J. M. Riemens, Samantha Stora, Mathilde Roche, Markus Leber, Steffi Riedel-Heller, Michael Wagner, Martin Scherer, Aimé Ravel, Clotilde Mircher, Cecile Cieuta-Walti, Sophie Durand…

    Citation: Clinical Epigenetics 2019 11:195

    Content type: Research

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  11. Differences between an individual’s estimated epigenetic gestational age (EGA) and their actual gestational age (GA) are defined as gestational age acceleration (GAA). GAA is associated with increased birthwei...

    Authors: Harold D. Bright, Laura D. Howe, Jasmine N. Khouja, Andrew J. Simpkin, Matthew Suderman and Linda M. O’Keeffe

    Citation: Clinical Epigenetics 2019 11:194

    Content type: Research

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  12. Sequencing technologies have changed not only our approaches to classical genetics, but also the field of epigenetics. Specific methods allow scientists to identify novel genome-wide epigenetic patterns of DNA...

    Authors: Ieva Rauluseviciute, Finn Drabløs and Morten Beck Rye

    Citation: Clinical Epigenetics 2019 11:193

    Content type: Review

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  13. The epigenome plays a key role in cancer heterogeneity and drug resistance. Hence, a number of epigenetic inhibitors have been developed and tested in cancers. The major focus of most studies so far has been o...

    Authors: Chiara Facciotto, Julia Casado, Laura Turunen, Suvi-Katri Leivonen, Manuela Tumiati, Ville Rantanen, Liisa Kauppi, Rainer Lehtonen, Sirpa Leppä, Krister Wennerberg and Sampsa Hautaniemi

    Citation: Clinical Epigenetics 2019 11:192

    Content type: Methodology

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  14. Aberrant DNA methylation is induced by aging and chronic inflammation in normal tissues. The induction by inflammation is widely recognized as acceleration of age-related methylation. However, few studies addr...

    Authors: Satoshi Yamashita, Sohachi Nanjo, Emil Rehnberg, Naoko Iida, Hideyuki Takeshima, Takayuki Ando, Takao Maekita, Toshiro Sugiyama and Toshikazu Ushijima

    Citation: Clinical Epigenetics 2019 11:191

    Content type: Research

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  15. A subset of individuals affected by imprinting disorders displays multi-locus imprinting disturbances (MLID). MLID has been associated with maternal-effect variants that alter the maintenance of methylation at...

    Authors: Angela Sparago, Ankit Verma, Maria Grazia Patricelli, Laura Pignata, Silvia Russo, Luciano Calzari, Naomi De Francesco, Rosita Del Prete, Orazio Palumbo, Massimo Carella, Deborah J. G. Mackay, Faisal I. Rezwan, Claudia Angelini, Flavia Cerrato, Maria Vittoria Cubellis and Andrea Riccio

    Citation: Clinical Epigenetics 2019 11:190

    Content type: Short report

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  16. Identifying subjects with a high risk of ischemic stroke is fundamental for prevention of the disease. Both genetic and environmental risk factors contribute to ischemic stroke, but the underlying epigenetic m...

    Authors: Xueying Qin, Jin Li, Tao Wu, Yiqun Wu, Xun Tang, Pei Gao, Lin Li, Mengying Wang, Yao Wu, Xiaowen Wang, Dafang Chen and Yonghua Hu

    Citation: Clinical Epigenetics 2019 11:189

    Content type: Research

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  17. Until today, adult and pediatric clinical trials investigating single-agent or combinatorial HDAC inhibitors including vorinostat in solid tumors have largely failed to demonstrate efficacy. These results may ...

    Authors: Cornelis M. van Tilburg, Till Milde, Ruth Witt, Jonas Ecker, Thomas Hielscher, Angelika Seitz, Jens-Peter Schenk, Juliane L. Buhl, Dennis Riehl, Michael C. Frühwald, Arnulf Pekrun, Claudia Rossig, Regina Wieland, Christian Flotho, Uwe Kordes, Bernd Gruhn…

    Citation: Clinical Epigenetics 2019 11:188

    Content type: Research

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  18. The role of DNA methylation in aging has been widely studied. However, epigenetic mutations, here defined as aberrant methylation levels compared to the distribution in a population, are less understood. Hence...

    Authors: Yunzhang Wang, Robert Karlsson, Juulia Jylhävä, Åsa K. Hedman, Catarina Almqvist, Ida K. Karlsson, Nancy L. Pedersen, Malin Almgren and Sara Hägg

    Citation: Clinical Epigenetics 2019 11:187

    Content type: Research

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  19. Emerging evidence indicates that dysregulation of microRNAs (miRNAs) contributes to cervical cancer (CC) tumorigenesis and development. Previous work showed that miR-484 which regulated the EMT process was obv...

    Authors: Yang Hu, Fuxia Wu, Yankun Liu, Qian Zhao and Hua Tang

    Citation: Clinical Epigenetics 2019 11:186

    Content type: Research

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  20. Molecular signatures are being increasingly incorporated into cancer classification systems. DNA methylation-based central nervous system (CNS) tumor classification is being recognized as having the potential ...

    Authors: Shirin Karimi, Jeffrey A. Zuccato, Yasin Mamatjan, Sheila Mansouri, Suganth Suppiah, Farshad Nassiri, Phedias Diamandis, David G. Munoz, Kenneth D. Aldape and Gelareh Zadeh

    Citation: Clinical Epigenetics 2019 11:185

    Content type: Research

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  21. Recent studies suggested that ZMYND10 is a potential tumor suppressor gene in multiple tumor types. However, the mechanism by which ZMYND10 inhibits breast cancer remains unclear. Here, we investigated the role a...

    Authors: Yan Wang, Liangying Dan, Qianqian Li, Lili Li, Lan Zhong, Bianfei Shao, Fang Yu, Sanxiu He, Shaorong Tian, Jin He, Qian Xiao, Thomas C. Putti, Xiaoqian He, Yixiao Feng, Yong Lin and Tingxiu Xiang

    Citation: Clinical Epigenetics 2019 11:184

    Content type: Research

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  22. Cancer still is one of the leading causes of death and its death toll is predicted to rise further. We identified earlier the potential tumour suppressor zygote arrest 1 (ZAR1) to play a role in lung carcinoge...

    Authors: Verena Deutschmeyer, Janina Breuer, Sara K. Walesch, Anna M. Sokol, Johannes Graumann, Marek Bartkuhn, Thomas Boettger, Oliver Rossbach and Antje M. Richter

    Citation: Clinical Epigenetics 2019 11:182

    Content type: Research

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  23. Obesity is a major worldwide threat to human health. Increasing evidence indicates that epigenetic modifications have a major impact on the natural history of this disorder. Ankyrin Repeat Domain 26 (Ankrd26) is ...

    Authors: Antonella Desiderio, Michele Longo, Luca Parrillo, Michele Campitelli, Giuseppe Cacace, Sonia de Simone, Rosa Spinelli, Federica Zatterale, Serena Cabaro, Pasquale Dolce, Pietro Formisano, Marco Milone, Claudia Miele, Francesco Beguinot and Gregory A. Raciti

    Citation: Clinical Epigenetics 2019 11:181

    Content type: Research

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  24. Epigenetic mechanisms provide an interface between environmental factors and the genome and are influential in various diseases. These mechanisms, including DNA methylation, influence the regulation of develop...

    Authors: Ji Hyae Lim, Yu-Jung Kang, Bom Yi Lee, You Jung Han, Jin Hoon Chung, Moon Young Kim, Min Hyoung Kim, Jin Woo Kim, Youl-Hee Cho and Hyun Mee Ryu

    Citation: Clinical Epigenetics 2019 11:180

    Content type: Research

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  25. Cisplatin-based chemotherapy (CBCT) is part of standard treatment of several cancers. In testicular cancer (TC) survivors, an increased risk of developing metabolic syndrome (MetS) is observed. In this epigeno...

    Authors: Cecilie Bucher-Johannessen, Christian M. Page, Trine B. Haugen, Marcin W. Wojewodzic, Sophie D. Fosså, Tom Grotmol, Hege S. Haugnes and Trine B. Rounge

    Citation: Clinical Epigenetics 2019 11:179

    Content type: Research

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  26. Gingivo-buccal oral squamous cell carcinoma (OSCC-GB) is the most common cancer among men in India and is associated with high mortality. Although OSCC-GB is known to be quite different from tongue cancer in i...

    Authors: Debodipta Das, Sahana Ghosh, Arindam Maitra, Nidhan K. Biswas, Chinmay K. Panda, Bidyut Roy, Rajiv Sarin and Partha P. Majumder

    Citation: Clinical Epigenetics 2019 11:178

    Content type: Research

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  27. In order to gain insight into the contribution of DNA methylation to disease progression of chronic lymphocytic leukemia (CLL), using 450K Illumina arrays, we determined the DNA methylation profiles in paired ...

    Authors: Maria Tsagiopoulou, Nikos Papakonstantinou, Theodoros Moysiadis, Larry Mansouri, Viktor Ljungström, Martí Duran-Ferrer, Andigoni Malousi, Ana C. Queirós, Karla Plevova, Sujata Bhoi, Panagoula Kollia, David Oscier, Achilles Anagnostopoulos, Livio Trentin, Matthias Ritgen, Sarka Pospisilova…

    Citation: Clinical Epigenetics 2019 11:177

    Content type: Research

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  28. Adolescence is a period characterized by major biological development, which may be associated with changes in DNA methylation (DNA-M). However, it is unknown to what extent DNA-M varies from pre- to post-adol...

    Authors: Luhang Han, Hongmei Zhang, Akhilesh Kaushal, Faisal I. Rezwan, Latha Kadalayil, Wilfried Karmaus, A. John Henderson, Caroline L. Relton, Susan Ring, S. Hasan Arshad, Susan L. Ewart and John W. Holloway

    Citation: Clinical Epigenetics 2019 11:176

    Content type: Research

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  29. Lung (LC), prostate (PCa) and colorectal (CRC) cancers are the most incident in males worldwide. Despite recent advances, optimal population-based cancer screening methods remain an unmet need. Due to its earl...

    Authors: Vera Constâncio, Sandra P. Nunes, Catarina Moreira-Barbosa, Rui Freitas, Jorge Oliveira, Inês Pousa, Júlio Oliveira, Marta Soares, Carlos Gonçalves Dias, Teresa Dias, Luís Antunes, Rui Henrique and Carmen Jerónimo

    Citation: Clinical Epigenetics 2019 11:175

    Content type: Research

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  30. The flexibility of the epigenome has generated an enticing argument to explore its reversion through pharmacological treatments as a strategy to ameliorate disease phenotypes. All three families of epigenetic ...

    Authors: A. Ganesan, Paola B. Arimondo, Marianne G. Rots, Carmen Jeronimo and María Berdasco

    Citation: Clinical Epigenetics 2019 11:174

    Content type: Review

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  31. Glioblastoma (GBM) is the most lethal and aggressive malignant primary brain tumor in adults. After surgical resection of the tumor, the patient typically should be subjected to chemotherapy (temozolomide, TMZ...

    Authors: Giulia Stazi, Ludovica Taglieri, Alice Nicolai, Annalisa Romanelli, Rossella Fioravanti, Stefania Morrone, Manuela Sabatino, Rino Ragno, Samanta Taurone, Marcella Nebbioso, Raffaella Carletti, Marco Artico, Sergio Valente, Susanna Scarpa and Antonello Mai

    Citation: Clinical Epigenetics 2019 11:173

    Content type: Research

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  32. There is solid evidence that obesity induces the acceleration of liver epigenetic aging. However, unlike easily accessible blood or subcutaneous adipose tissue, little is known about the impact of obesity on e...

    Authors: Juan de Toro-Martín, Frédéric Guénard, André Tchernof, Frédéric-Simon Hould, Stéfane Lebel, François Julien, Simon Marceau and Marie-Claude Vohl

    Citation: Clinical Epigenetics 2019 11:172

    Content type: Research

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  33. Constitutional MLH1 methylation (epimutation) is a rare cause of Lynch syndrome. Low-level methylation (≤ 10%) has occasionally been described. This study aimed to identify low-level constitutional MLH1 epimutati...

    Authors: Estela Dámaso, Júlia Canet-Hermida, Gardenia Vargas-Parra, Àngela Velasco, Fátima Marín, Esther Darder, Jesús del Valle, Anna Fernández, Àngel Izquierdo, Gemma Mateu, Glòria Oliveras, Carmen Escribano, Virgínia Piñol, Hugo-Ikuo Uchima, José Luis Soto, Megan Hitchins…

    Citation: Clinical Epigenetics 2019 11:171

    Content type: Short report

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  34. Endometrial cancer is a common gynecologic cancer. Noninvasive molecular biomarkers for triage of high-risk patients for invasive procedures are needed. Based on the success of cytological Pap smear screening,...

    Authors: Phui-Ly Liew, Rui-Lan Huang, Tzu-I Wu, Chi-Chun Liao, Chien-Wen Chen, Po-Hsuan Su, Hui-Chen Wang, Yu-Chun Weng and Hung-Cheng Lai

    Citation: Clinical Epigenetics 2019 11:170

    Content type: Research

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  35. Perinatal depressive symptoms have been linked to adverse maternal and infant health outcomes. The etiology associated with perinatal depressive psychopathology is poorly understood, but accumulating evidence ...

    Authors: Dana M. Lapato, Roxann Roberson-Nay, Robert M. Kirkpatrick, Bradley T. Webb, Timothy P. York and Patricia A. Kinser

    Citation: Clinical Epigenetics 2019 11:169

    Content type: Research

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  36. An epigenetic field of cancer susceptibility exists for prostate cancer (PC) that gives rise to multifocal disease in the peripheral prostate. In previous work, genome-wide DNA methylation profiling identified...

    Authors: Bing Yang, Tyler Etheridge, Johnathon McCormick, Adam Schultz, Tariq A. Khemees, Nathan Damaschke, Glen Leverson, Kaitlin Woo, Geoffrey A. Sonn, Eric A. Klein, Mike Fumo, Wei Huang and David F. Jarrard

    Citation: Clinical Epigenetics 2019 11:168

    Content type: Research

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  37. Glial cells in the central nervous system play a key role in neuroinflammation and subsequent central sensitization to pain. They are therefore involved in the development of persistent pain. One of the main s...

    Authors: Dario Kringel, Mari A. Kaunisto, Eija Kalso and Jörn Lötsch

    Citation: Clinical Epigenetics 2019 11:167

    Content type: Research

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  38. Ovarian cancer (OC) is the most lethal gynecological cancer, worldwide, largely due to its vague and nonspecific early stage symptoms, resulting in most tumors being found at advanced stages. Moreover, due to ...

    Authors: Tzu-I Wu, Rui-Lan Huang, Po-Hsuan Su, Shih-Peng Mao, Chen-Hsuan Wu and Hung-Cheng Lai

    Citation: Clinical Epigenetics 2019 11:166

    Content type: Research

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  39. Euchromatic histone-lysine-N-methyltransferases 1 and 2 (EHMT1/2, aka GLP/G9A) catalyze dimethylation of histone H3 lysine 9 (H3K9me2) and have roles in epigenetic silencing of gene expression. EHMT1/2 also have ...

    Authors: Zachary L. Watson, Tomomi M. Yamamoto, Alexandra McMellen, Hyunmin Kim, Connor J. Hughes, Lindsay J. Wheeler, Miriam D. Post, Kian Behbakht and Benjamin G. Bitler

    Citation: Clinical Epigenetics 2019 11:165

    Content type: Research

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  40. Late-onset Alzheimer’s disease (AD) is a complex multifactorial affliction, the pathogenesis of which is thought to involve gene-environment interactions that might be captured in the epigenome. The present st...

    Authors: Roy Lardenoije, Janou A. Y. Roubroeks, Ehsan Pishva, Markus Leber, Holger Wagner, Artemis Iatrou, Adam R. Smith, Rebecca G. Smith, Lars M. T. Eijssen, Luca Kleineidam, Amit Kawalia, Per Hoffmann, Tobias Luck, Steffi Riedel-Heller, Frank Jessen, Wolfgang Maier…

    Citation: Clinical Epigenetics 2019 11:164

    Content type: Research

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  41. Recently, an alcohol predictor was developed using DNA methylation at 144 CpG sites (DNAm-Alc) as a biomarker for improved clinical or epidemiologic assessment of alcohol-related ill health. We validate the pe...

    Authors: Paul Darius Yousefi, Rebecca Richmond, Ryan Langdon, Andrew Ness, Chunyu Liu, Daniel Levy, Caroline Relton, Matthew Suderman and Luisa Zuccolo

    Citation: Clinical Epigenetics 2019 11:163

    Content type: Research

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  42. Over the last several decades, the average age of first-time mothers has risen steadily. With increasing maternal age comes a decrease in fertility, which in turn has led to an increase in the use of assisted ...

    Authors: Audrey J. Kindsfather, Megan A. Czekalski, Catherine A. Pressimone, Margaret P. Erisman and Mellissa R. W. Mann

    Citation: Clinical Epigenetics 2019 11:162

    Content type: Research

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  43. The T cell immunoglobulin and mucin-domain containing-3 receptor TIM-3 (also known as hepatitis A virus cellular receptor 2, encoded by HAVCR2) and its ligand galectin 9 (LGALS9) are promising targets for immune ...

    Authors: Tobias A. W. Holderried, Luka de Vos, Emma Grace Bawden, Timo J. Vogt, Joern Dietrich, Romina Zarbl, Friedrich Bootz, Glen Kristiansen, Peter Brossart, Jennifer Landsberg and Dimo Dietrich

    Citation: Clinical Epigenetics 2019 11:161

    Content type: Research

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  44. The metabolic syndrome (MetS) is a collection of metabolic disturbances that can lead to various cardiovascular diseases. Previous studies have shown a more adverse metabolic risk profile is associated with mo...

    Authors: Drew R. Nannini, Brian T. Joyce, Yinan Zheng, Tao Gao, Lei Liu, Grace Yoon, Tianxiao Huan, Jiantao Ma, David R. Jacobs Jr, John T. Wilkins, Jim Ren, Kai Zhang, Sadiya S. Khan, Norrina Bai Allen, Steve Horvath, Donald M. Lloyd-Jones…

    Citation: Clinical Epigenetics 2019 11:160

    Content type: Research

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  45. Diuron is an environmental component listed as a likely human carcinogen. Several other studies report that diuron can be oncogenic for bladder, urothelial, skin, and mammary cells. No study mentions the putat...

    Authors: Joséphine Briand, Arulraj Nadaradjane, Gwenola Bougras-Cartron, Christophe Olivier, François M. Vallette and Pierre-François Cartron

    Citation: Clinical Epigenetics 2019 11:159

    Content type: Research

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  46. Early detection plays an essential role to reduce colorectal cancer (CRC) mortality. While current screening methods suffer from poor compliance, liquid biopsy-based strategies for cancer detection is rapidly ...

    Authors: Sarah Østrup Jensen, Nadia Øgaard, Mai-Britt Worm Ørntoft, Mads Heilskov Rasmussen, Jesper Bertram Bramsen, Helle Kristensen, Peter Mouritzen, Mogens Rørbæk Madsen, Anders Husted Madsen, Kåre Gotschalck Sunesen, Lene Hjerrild Iversen, Søren Laurberg, Ib Jarle Christensen, Hans Jørgen Nielsen and Claus Lindbjerg Andersen

    Citation: Clinical Epigenetics 2019 11:158

    Content type: Research

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  47. Recently, it was shown that the epigenetic age of non-small cell lung cancer (NSCLC) tissues is different from the chronological age of patients. Here, we demonstrate that Regucalcin and Survivin, molecules wh...

    Authors: Dörte Nitschkowski, Sebastian Marwitz, Sousana A. Kotanidou, Martin Reck, Christian Kugler, Klaus F. Rabe, Ole Ammerpohl and Torsten Goldmann

    Citation: Clinical Epigenetics 2019 11:157

    Content type: Letter to the Editor

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  48. SETD1B is a component of a histone methyltransferase complex that specifically methylates Lys-4 of histone H3 (H3K4) and is responsible for the epigenetic control of chromatin structure and gene expression. De...

    Authors: I. M. Krzyzewska, S. M. Maas, P. Henneman, K. v. d. Lip, A. Venema, K. Baranano, A. Chassevent, E. Aref-Eshghi, A. J. van Essen, T. Fukuda, H. Ikeda, M. Jacquemont, H.-G. Kim, A. Labalme, S. M. E. Lewis, G. Lesca…

    Citation: Clinical Epigenetics 2019 11:156

    Content type: Research

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  49. The glucocorticoid receptor (NR3C1, GR) is frequently downregulated in breast tumors, and evidence suggests it acts as a tumor suppressor in estrogen receptor-positive (ER+) breast cancer. We previously found tha...

    Authors: Hilary Snider, Brithica Villavarajan, Yingwei Peng, Lois E. Shepherd, Andrew C. Robinson and Christopher R. Mueller

    Citation: Clinical Epigenetics 2019 11:155

    Content type: Research

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