Table 2 Estimated proportion of leukocyte subtypes within isolated cell-type fractions from nonsmokers and smokers
Cell type | Subtype | Nonsmokers Percent within the isolated fraction | Smokers Percent within the isolated fraction | Difference | p* | p-adj** |
|---|---|---|---|---|---|---|
(Mean ± S.E.M.) | (Mean ± S.E.M.) | (Mean) (%) | ||||
B Cell (CD19+) | Naïve B | 60.0% ± 1.9% | 52.8% ± 2.2% |  − 7.20 | 0.014 | 0.033 |
Memory B | 31.3% ± 1.8% | 36.0% ± 2.2% | 4.70 | 0.096 | 0.12 | |
Granulocyte (CD15+) | Neutrophils | 95.0% ± 0.3% | 93.6% ± 0.6% |  − 1.40 | 0.028 | 0.054 |
Basophils | 0.1% ± 0.0% | 0.2% ± 0.1% | 0.10 | 0.134 | 0.348 | |
Eosinophils | 0.0% ± 0.0% | 0.0% ± 0.0% | 0.00 | 0.334 | 0.26 | |
Monocyte (CD14+) | Monocytes | 93.8% ± 0.5% | 93.1% ± 0.4% |  − 0.60 | 0.332 | 0.684 |
NK Cell (CD56+) | Natural killer | 49.4% ± 1.7% | 46.5% ± 1.8% |  − 2.90 | 0.244 | 0.231 |
CD4T Cell (CD4+) | Naïve CD4T | 35.1% ± 2.0% | 30.2% ± 2.0% |  − 4.90 | 0.09 | 0.413 |
Memory CD4T | 49.2% ± 1.8% | 52.1% ± 1.7% | 2.90 | 0.253 | 0.739 | |
Regulatory T (Treg) | 5.3% ± 0.4% | 5.6% ± 0.5% | 0.30 | 0.641 | 0.544 | |
CD8T Cell (CD8+) | Naïve CD8T | 37.6% ± 2.2% | 31.3% ± 2.7% |  − 6.40 | 0.07 | 0.319 |
Memory CD8T | 45.7% ± 2.0% | 48.9% ± 2.4% | 3.20 | 0.31 | 0.648 |