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Fig. 8 | Clinical Epigenetics

Fig. 8

From: Histone lysine methyltransferase SMYD3 promotes oral squamous cell carcinoma tumorigenesis via H3K4me3-mediated HMGA2 transcription

Fig. 8

The regulatory association of SMYD3 with HMGA2 could be universal. A In the TCGA pan-cancer dataset, SMYD3 was positively correlated with HMGA2 expression in most tumor tissues. B In the GTEx database, SMYD3 was positively correlated with HMGA2 expression in most normal tissues. C In the CCLE database, SMYD3 was positively correlated with HMGA2 expression in most upper respiratory gastrointestinal tract tumor cell lines. D Graphical abstract for SMYD3 promoting tumorigenesis of OSCC

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