Table 1 Demographic and reproductive characteristics of the women selected for and included in our pilot study on TRAP exposure, supplemental folic acid intake, and granulosa cell DNA methylation
Median ± IQR or N (%) | Women with GC samples sent for analysis (n = 132) | Women included in the GC DNAm analysis (n = 61) |
|---|---|---|
Demographic characteristics | Â | Â |
Age, years | 34.8 ± 5.8 | 34.8 ± 5.7 |
BMI, kg/m2 | 23.1 ± 5.0 | 24.2 ± 5.5 |
 Smoking status |  |  |
   Never | 96 (72.7) | 45 (73.8) |
   Past/Current | 36 (27.3) | 16 (26.2) |
 Race |  |  |
   White | 112 (84.9) | 53 (86.9) |
   Black | 2 (1.5) | 0 (0.0) |
   Asian | 14 (10.6) | 5 (8.2) |
   Other | 4 (3.0) | 3 (4.9) |
 Ethnicity |  |  |
   Hispanic | 10 (7.6) | 4 (6.6) |
   Non-hispanic | 122 (92.4) | 57 (93.4) |
 Education |  |  |
   High school graduate | 4 (3.0) | 2 (3.3) |
   Some college | 7 (5.3) | 3 (4.9) |
   College graduate | 45 (34.1) | 23 (37.7) |
   Graduate degree | 76 (57.6) | 33 (54.1) |
 NO2 Exposure, ppb |  |  |
   High | 42.0 ± 16.5 | 43.3 ± 27.7 |
   Low | 9.7 ± 6.4 | 9.2 ± 5.1 |
 Supplemental folic acid intake, µg/day |  |  |
   High | 800.2 ± 200.0 | 829.8 ± 200.0 |
   Low | 228.6 ± 342.9 | 230.6 ± 342.9 |
Reproductive characteristics | Â | Â |
 Infertility diagnosis |  |  |
   Male | 41 (31.1) | 17 (27.8) |
   Female | 41 (31.1) | 22 (36.1) |
   Unexplained | 50 (37.9) | 22 (36.1) |
Protocol | Â | Â |
   Antagonist | 15 (11.4) | 6 (9.8) |
   Flare | 23 (17.4) | 10 (16.4) |
   Luteal phase | 94 (71.2) | 45 (73.8) |