The role of angiotensin I-converting enzyme gene polymorphism and global DNA methylation in the negative associations between urine di-(2-ethylhexyl) phthalate metabolites and serum adiponectin in a young Taiwanese population

Table 4 Unstandardized regression coefficients (standard error) of ln-adiponectin levels with a one-unit increase in ln-MEHP concentration by different categories of 5mdC/dG and ACE gene polymorphism and their cross product in analysis

	No	Adjusted β (SE)	P value	P for interaction
5mdC/dG				0.038
Total	353	− 0.078 (0.021)	< 0.001
5mdC/dG ≤ 50th percentile	176	− 0.049 (0.030)	0.100
5mdC/dG > 50th percentile	177	− 0.095 (0.031)	0.002
ACE gene phenotype				0.060
Total	438	− 0.078 (0.019)	< 0.001
D/D	52	− 0.128 (0.063)	0.068
I/D	179	− 0.021 (0.027)	0.435
I/I	207	− 0.098 (0.028)	< 0.001

Model adjusted for age, gender, BMI z score, smoking status, drinking status, household income

ISSN: 1868-7083