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Table 1 Geometric means (S.E.) of the urine DEHP metabolites, serum adiponectin, and 5mdC/dG in different subgroups

From: The role of angiotensin I-converting enzyme gene polymorphism and global DNA methylation in the negative associations between urine di-(2-ethylhexyl) phthalate metabolites and serum adiponectin in a young Taiwanese population

 

n

MEHP (μg/g creatinine)

MEHHP (μg/g creatinine)

MEOHP (μg/g creatinine)

n

Adiponectin (ng/mL)

n

5mdC/dG (%)

Overall Age (year)

699

5.12 (1.10)

27.37 (1.04)

16.87 (1.04)

450

6484.05 (1.05)

626

2.11 (1.02)

12–19

196

9.02 (1.17)**

27.09 (1.08)

16.12 (1.08)

92

5675.42 (1.13)

177

2.06(1.05)

20–39

503

4.10 (1.13)**

27.49 (1.04)

17.17 (1.04)

358

6710.31 (1.06)

449

2.62 (1.03)

Gender

Male

286

4.22 (1.17)

25.73 (1.06)

15.25 (1.06)*

193

5460.52 (1.07)*

255

2.14 (1.04)

Female

413

5.85 (1.13)

25.56 (1.05)

18.09 (1.05)*

257

7377.57 (1.07)*

371

2.09 (1.03)

Household income (TWD)

 < 50,000 per month

266

4.15 (1.18)

26.09 (1.07)

15.97 (1.07)

178

7215.60 (1.09)

227

2.10 (1.04)

 ≥ 50,000 per month

432

5.81 (1.13)

28.22 (1.04)

17.47 (1.04)

272

6046.29 (1.06)

398

2.11 (1.03)

Smoking status

Not active smokers

578

5.51 (1.11)

27.91 (1.04)

17.22 (1.04)

371

6658.17 (1.06)

515

2.12 (1.03)

Active smokers

121

3.61 (1.28)

24.96 (1.10)

15.29 (1.09)

79

5726.73 (1.12)

111

2.08 (1.06)

Current alcohol consumption

No

635

4.92 (1.11)

27.52 (1.04)

16.98 (1.04)

411

6506.78 (1.05)

569

2.07 (1.03)*

Yes

63

7.54 (1.35)

26.12 (1.10)

15.89 (1.10)

39

6248.52 (1.19)

56

2.50 (1.08)*

BMI z score (kg/m2)

 < − 0.212

348

4.66 (1.15)

29.34 (1.05)

18.47 (1.06)*

218

8787.99 (1.08)**

316

2.00 (1.04)*

 ≥ − 0.212

351

5.62 (1.15)

25.55 (1.05)

15.43 (1.05)*

232

4874.62 (1.06)**

310

2.23 (1.03)*

Hypertension

No

646

4.96 (1.11)

27.55 (1.40)

17.00 (1.04)

407

6756.77 (1.05)*

581

2.11 (1.03)

Yes

53

7.57 (1.47)

25.34 (1.15)

15.41 (1.15)

43

4391.39 (1.17)*

45

2.13 (1.10)

ACE genotypes

D/D

73

6.04 (1.36)

31.01 (1.12)

18.70 (1.12)

52

5947.94 (1.18)

62

2.28 (1.08)

I/D

292

5.30 (1.16)

27.42 (1.06)

16.94 (1.06)

183

6122.95 (1.07)

263

2.14 (1.04)

I/I

333

4.75 (1.15)

26.57 (1.05)

16.42 (1.05)

214

6999.54 (1.08)

301

2.04 (1.03)

  1. Tests by Student’s two-tailed t-test or one-way analysis of variance. *P < 0.05 **P < 0.001
  2. ACE Angiotensin-converting enzyme; DEHP Di-(2-ethylhexyl) phthalate; MEHP Mono(2-ethylhexyl) phthalate; MEHHP Mono(2-ethyl-5-hydroxyhexyl) phthalate; MEOHP Mono(2-ethyl-5-oxohexyl) phthalate; TWD New Taiwan dollar