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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Risk assessment of assisted reproductive technology and parental age at childbirth for the development of uniparental disomy-mediated imprinting disorders caused by aneuploid gametes

Fig. 2

Comparison of maternal childbearing age. A The distribution of maternal childbearing age in the patients with aneuploid UPD-IDs between 1991 and 2017. Green dots indicate the maternal age of the patients with aneuploid UPD-IDs in each year. The black line indicates the median age of the general population and the yellow area indicates the 2.5th to 97.5th percentiles of the general population. B The distribution of maternal childbearing age in the patients with epi-IDs between 1991 and 2017, modified from Fig. 3 in reference #14. Blue dots indicate the maternal age of the patients with epi-IDs in each year. The black line indicates the median age of the general population and the yellow area indicates the 2.5th to 97.5th percentiles of the general population. C The distribution of maternal age in patients with aneuploid UPD-IDs and epi-IDs. Black bars indicate the median maternal age of patients in each group. UPD-IDs, uniparental disomy-mediated imprinting disorders; epi-IDs, epimutation-mediated imprinting disorders

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