Fig. 2

Low-dose 5-azacytidine induces DNA demethylation without DNA damage. A Phospho-H2AX expression in the indicated DLBCL cell lines was detected using Western blotting; UV-treated cell was serving as positive control. B 5mC DNA dot blots showing the effect of low-dose 5-azacytidine on the global DNA methylation level for each cell line, and methylene blue served as the DNA loading control. C DNMT1 protein levels were detected using Western blotting in PBS or 5-azacytidine-treated cells