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Fig. 3 | Clinical Epigenetics

Fig. 3

From: E3 ubiquitin ligase RNF180 prevents excessive PCDH10 methylation to suppress the proliferation and metastasis of gastric cancer cells by promoting ubiquitination of DNMT1

Fig. 3

PCDH10 overexpression inhibits GC progression in vitro and in vivo. A, B CCK-8 assay and colony formation was performed to determine the effect of PCDH10 overexpression on cell proliferation. C, D, E The effects of PCDH10 overexpression on cellular apoptosis and cell cycle were detected by flow cytometry. F, G PCDH10 stably overexpressed HGC27 cells and control cells were injected subcutaneously into nude mice (n = 5). *p < 0.05, ***p < 0.001, ****p < 0.0001, N.S., not significant

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Clinical Epigenetics

ISSN: 1868-7083

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