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Fig. 7 | Clinical Epigenetics

Fig. 7

From: Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome

Fig. 7

Butyric acid improves ovarian inflammation in PCOS model mice. A Photomicrographs of representative ovarian cross section from four groups: Control group, PCOS group, PCOS + Low BA group, and PCOS + High BA group. *: developing follicles; ●: corpus luteum; #: cystic follicles. Bar = 500 μm. B Serum hormone level of mice in each group. Bars represent means ± SD, n = 5. *P < 0.05. C, D PPAR-γ and GLUT4 in ovarian tissue of mice in each group protein expression level. Bars represent means ± SD, n = 5. *P < 0.05. E, F NLRP3, TNF-α and IL-6 in ovarian tissue of mice in each group protein expression level. Bars represent means ± SD, n = 5. *P < 0.05

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Clinical Epigenetics

ISSN: 1868-7083

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