Skip to main content
Fig. 4 | Clinical Epigenetics

Fig. 4

From: Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome

Fig. 4

Butyric acid improves glucose transport in inflammatory KGN cells. A, B Glucose uptake of KGN cells was detected by 2-NBDG staining. Fluorescence intensity of 2-NBDG (green color) was determined by Image J software. Each value in the graph represents the relative units (fluorescence/cell numbers). Scale bar, 100 μm. *P < 0.05, **P < 0.01. C, D The distribution of GLUT4 in KGN cells was showed by immunofluorescence. Scale bar, 20 μm. *P < 0.05, **P < 0.01. E, F The protein expression of PPAR-γ1/2 and GLUT4 in the KGN cells after treated with butyric acid. *P < 0.05, n = 3. G The mRNA expression of PPAR-γ and GLUT4 in KGN cells after treated with butyric acid.. *P < 0.05, ** < 0.01, n = 3

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us