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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome

Fig. 2

Composition and Linear discriminant analysis of gut microbiota among three groups. A Composition of species at family level among three groups. B Linear discriminant analysis (LDA) discriminant histogram of gut microbiota in three groups. Identification of the bacterial taxa with statistically significant difference between groups using LEfSe software and LDA. Taxa enriched in Control, FAT-PCOS, and HA-PCOS group are colored by red, green, and blue respectively (LDA > 2.0 and P < 0.05), the relative abundance of thesebiomarkers are shown in the histogram (mean and standard deviation values are plotted) under the corresponding cladogram. C The content of short chain fatty acids in serum of three groups of patients. *P < 0.05. D Spearman correlation heat map between clinical parameters and flora. The color of spots represents the Spearman correlation R-value between each bacterial taxa and clinical parameters. *P < 0.05

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