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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Peritoneal cell-free DNA as a sensitive biomarker for detection of peritoneal metastasis in colorectal cancer: a prospective diagnostic study

Fig. 2

The mutational profiling of cfDNA in matched FLD and TIS of PM and non-PM patients were compared by cluster plot. More mutations were shown in both FLD and TIS of PM patients, while no mutant in FLD in the major of non-PM patients were observed. The top five frequent gene mutations were KRAS (44%), TP53 (62%), APC(50%), PIK3CA(11%) and SMAD4(20%). Alleviations: TNM-TNM staging system, CN- copy number, TIS- tissue sample, FLD- peritoneal lavage fluid

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Clinical Epigenetics

ISSN: 1868-7083

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