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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Epigenetically regulated gene expression profiles decipher four molecular subtypes with prognostic and therapeutic implications in gastric cancer

Fig. 6

The further decipherment of immune landscape for GC subtypes of the TCGA dataset. A Heatmap of the remaining six immune cell infiltration assessment algorithms (EPIC, ESTIMATE, MCPcounter, Quantiseq, TIMER, and xCell) for our subtypes. B The performances of GC subtypes during the cancer immunity cycle. C The performance of GC subtypes in tumor immune dysfunction and exclusion (TIDE) of the TCGA cohort. D SubMap analysis reveals the similarity of GEPs between GC subtypes of TCGA and 6 GEO immunotherapy cohorts. ‘R’ represents responders, and ‘NR’ represents non-responders. ‘ns’ represents no significance, *P < 0.05, **P < 0.01, ***P < 0.001,  ****P < 0.0001

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