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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Epigenetically regulated gene expression profiles decipher four molecular subtypes with prognostic and therapeutic implications in gastric cancer

Fig. 2

Screening of METcor and MIRcor genes in TCGA-STAD. A Overlap of the METcor and MIRcor genes. B, C Proportional frequency of promoter CpG sites based on their distance relative to CpG islands and genomic positions, respectively. Shore, 0–2 kb upstream or downstream from CpG island; Shelf, 2–4 kbp upstream or downstream from CpG island; Opensea, other regions of the genome. D, E Functional enrichment analysis of the METcor and MIRcor genes. F Correlation between the frequencies of aberrant METcor and MIRcor genes in each sample of the TCGA dataset. G Pairwise correlations among the frequencies of METcor_high, METcor_low, MIRcor_high and MIRcor_low genes, respectively

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