Skip to main content
Fig. 8 | Clinical Epigenetics

Fig. 8

From: Comprehensive analyses of molecular features, prognostic values, and regulatory functionalities of m6A-modified long non-coding RNAs in lung adenocarcinoma

Fig. 8

Construction of m6A-induced ceRNA Network. A The subcellular localization of 43 differentially m6A-modified lncRNAs according to RNALoate. B The construction process of the ceRNA network, which consisted of 11 correlative m6A regulators, seven differentially modified lncRNAs, 30 sponged miRNAs, and 110 targeted mRNAs. C The diagram of the ceRNA network. The lines connecting m6A regulators and lncRNAs represented RNA co-expression in TCGA-LUAD set (|r|> 0.3 and P < 0.001), and the red line represented the lncRNA-m6A regulator protein combination detected by CLIP-seq recorded in the POSTAR3 database. D The chart emphasized the dysregulated targeted mRNAs in LUAD, whose numbers of connecting nodes were greater than or equal to 3 in the ceRNA network. FC represented the expression fold change of T-median/N-median. WilcoxTest. ***P < 0.001

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us