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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Comprehensive analyses of molecular features, prognostic values, and regulatory functionalities of m6A-modified long non-coding RNAs in lung adenocarcinoma

Fig. 3

Characteristics of the m6A-modified lncRNA microarray in LUAD tumor tissues and adjacent normal tissues. A The source distribution of m6A-modified lncRNA transcripts. B The length distribution of m6A-modified lncRNA transcripts (≤ 3000 bp). C The chromosomal localization of m6A-modified lncRNA transcripts. D Volcano plot showed that in 2846 m6A-modified lncRNA transcripts, 143 were differentially modified (|log2FC|> 0.585, P < 0.05, unpaired t test), and 123 were hypermethylated and 20 were hypomethylated. E The methylation level heatmap of 143 differentially modified lncRNA transcripts. F Volcano plot showed that in 143 differentially modified lncRNA transcripts, 32 were upregulated and 48 were downregulated (|log2FC|> 1, P < 0.05, unpaired t test). G The expression level heatmap of 143 differentially modified lncRNA transcripts

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Clinical Epigenetics

ISSN: 1868-7083

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