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Table 2 CpG loci exhibit significant association between family income and breast tumor DNA methylation

From: An epigenome-wide analysis of socioeconomic position and tumor DNA methylation in breast cancer patients

 

Coefficient (2-levels)

p value (2-levels)

Coefficient (5-levels)

p value (5-levels)

Chr

MapInfo

Gene in proximity

Genomic Features

cg00452016

0.26

5.92E−09

0.08

5.50E−08

5

43603138

NNT

5′UTR

cg14216142

0.22

2.98E−08

0.05

1.77E−05

3

138313050

CEP70

5′UTR

cg08962709

0.14

3.81E−08

0.04

8.67E−07

4

95128673

SMARCAD1

TSS1500

cg10319857

− 0.05

5.53E−08

− 0.01

1.09E−06

16

69653345

NFAT5

5′UTR

cg05411428

0.17

5.57E−08

0.05

5.26E−06

2

64751054

AFTPH

TSS1500

cg08879724

0.17

6.36E−08

0.05

1.11E−06

3

156893035

  

cg01225298

0.08

6.91E−08

0.03

2.38E−07

X

132091287

HS6ST2

Body

cg00547727

− 0.05

7.12E−08

− 0.01

2.16E−06

16

714968

WDR90

Body

cg06060338

0.21

7.41E−08

0.06

9.61E−07

8

74884601

TCEB1

TSS1500

cg19935671

0.11

7.62E−08

0.03

1.01E−06

3

121468093

GOLGB1

5′UTR

cg23402769

0.15

8.28E−08

0.05

2.07E−07

7

16685581

BZW2

TSS200

cg16262415

0.11

1.00E−07

0.04

2.02E−07

1

211848604

NEK2

Body

cg12302560

− 0.06

1.09E−07

− 0.02

5.71E−06

1

6611319

NOL9

Body

cg05176996

0.21

1.14E−07

0.06

1.58E−06

9

98637794

C9orf130

TSS200

cg02847760

0.11

1.16E−07

0.03

3.09E−06

15

40453199

BUB1B

TSS200

cg04990372

0.11

1.24E−07

0.04

1.23E−08

20

47895899

MIR1259

TSS1500

cg14291066

0.15

1.26E−07

0.05

4.11E−07

18

5238200

C18orf18

TSS200

cg03170171

− 0.06

1.33E−07

− 0.02

1.11E−05

19

17389968

C19orf62

3′UTR

cg12051027

− 0.06

1.34E−07

− 0.02

1.95E−06

1

48931095

SPATA6

Body

cg01667837

0.16

1.45E−07

0.05

1.62E−07

7

124405605

GPR37

5′UTR

cg10838757

0.18

1.47E−07

0.05

5.99E−06

5

130507273

LYRM7

Body

cg20359202

− 0.05

1.56E−07

− 0.01

3.05E−06

4

40626144

RBM47

5′UTR

cg00391320

− 0.05

1.62E−07

− 0.02

2.04E−07

12

112127825

ACAD10

5′UTR

cg20705065

0.11

1.77E−07

0.03

1.91E−06

17

48074613

  

cg06526960

− 0.03

1.79E−07

− 0.01

1.18E−05

1

151336795

SELENBP1

3′UTR

  1. Linear regression was performed using limma to test associations between DNA methylation levels at each CpG site and family income levels (2- or 5-levels), adjusted for age at diagnosis (continuous values), race (Black vs. White), and tumor estrogen receptor (ER) status (positive vs. negative)
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Clinical Epigenetics

ISSN: 1868-7083

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