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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Sperm DNA methylation is predominantly stable in mice offspring born after transplantation of long-term cultured spermatogonial stem cells

Fig. 6

Multi-generational mouse model of SSCT offspring generation. F0—transplanted mice, F1—first generational born after SSCT, F2—second generational born from one SCCT-derived parent F2/M—F2 generated from the maternal line, F2/P—F2 generated from the paternal line. Sperm was collected from five males of each generated offspring for comparison of DNA methylation status (n = 3 in the F0, n = 5 per offspring subgroup in the F1 and F2)

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