Skip to main content
Fig. 3 | Clinical Epigenetics

Fig. 3

From: Sperm DNA methylation is predominantly stable in mice offspring born after transplantation of long-term cultured spermatogonial stem cells

Fig. 3

Differential analysis for DMRs of the SSCT F1 and F2 offspring compared to control F1. A Volcano plot shows the number of DMRs with changed patterns of methylation between SSCT samples and control samples significantly higher or lower than the 25% difference cut-off and considering a q-value threshold of 0.01. Values on the x- and y-axes are percent methylation differences and negative log10 of the corrected p-values, respectively. B The distribution of differentially methylated regions (DMRs) over DNA regions exons, introns, promoters and intergenic regions. F2/M—F2 generated from the maternal line, F2/P—F2 generated from the paternal line

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us