% of total | No. of articles | |
---|---|---|
Category | ||
Heart | 43.4 | 43 |
Vasculature | 32.3 | 32 |
Cardiovascular disease (CVD) | 12.1 | 12 |
Cardiovascular risk factors (CVRF) | 8.1 | 8 |
Other | 4.0 | 4 |
Tissue | ||
Blood | 76.8 | 76 |
Cardiac tissue excluding ventricles | 9.1 | 9 |
Cardiac ventricles | 6.1 | 6 |
Aorta | 5.1 | 5 |
Artery | 3.0 | 3 |
Measuring method* | ||
Illumina bead-based 450 k array | 46.5 | 46 |
Pyrosequencing | 12.1 | 12 |
Illumina bead-based 850 k array | 10.1 | 10 |
Whole-Genome Bisulfite Sequencing (WGBS) | 4.0 | 4 |
Illumina bead-based 27 k array | 3.0 | 3 |
Reduced representation bisulfite sequencing (RRBS) | 2.0 | 2 |
Radiolabeling | 2.0 | 2 |
Other | 18.2 | 18 |
Outcome | ||
Ischemic Stroke | 11.1 | 11 |
Atherosclerosis | 10.1 | 10 |
Incident CVD | 8.1 | 8 |
Incident MI | 8.1 | 8 |
Incident HF | 6.1 | 6 |
CAD | 5.1 | 5 |
Incident Dilated cardiomyopathy | 4.0 | 4 |
Acute coronary syndrome | 3.0 | 3 |
AFIB | 3.0 | 3 |
CHD | 3.0 | 3 |
Other | 38.4 | 38 |
Measuring type* | ||
Epigenome-wide methylation | 59.6 | 59 |
Specific gene methylation | 23.2 | 23 |
Global genome methylation | 8.1 | 8 |
Epigenetic clock methylation | 8.1 | 8 |
Specific CpG methylation | 2.0 | 2 |
Study location | ||
Asia | 38.4 | 38 |
Europe | 36.4 | 36 |
North and South America | 26.3 | 26 |
Australia | 1.0 | 1 |
Sex** | ||
Female | 54.0*** | 6986 |
Male | 46.0*** | 5963 |
Age range** | ||
0–30 years | 2.0 | 2 |
30–60 years | 23.2 | 23 |
60–100 years | 62.6 | 62 |
Sample size range** | ||
1–100 | 34.3 | 34 |
100–500 | 29.3 | 29 |
500–1000 | 15.2 | 15 |
1000–2000 | 7.1 | 7 |
2000–5000 | 10.1 | 10 |
≥ 5000 | 3.0 | 3 |