Fig. 5
From: Distinguishable DNA methylation defines a cardiac-specific epigenetic clock
Echocardiography distinguishes accelerated and decelerated AVR and CABG. At the bottom of each bar, the average value is reported. A SV: Stroke volume. No differences between AVR decelerated and CABG groups. However, significant differences arose in AVR accelerated compared to the others. B LVEDV: left ventricular end-diastolic volume. No differences between decelerated AVR and the CABG groups. On the other hand, the accelerated AVR revealed significant differences compared to all others. C LVESV: left ventricle end-systolic volume, differences emerged in the accelerated AVR vs. decelerated AVR and versus accelerated CABG. No differences were detected evaluating S: septal; LPVW: left posterior ventricular wall thickness; EF: ejection fraction; and LVSd: left systolic ventricle diameter (panels D, E, F, and H, respectively). Interestingly, panel G shows that in the accelerated AVRs, the LVDd: left ventricle diastolic diameter is significantly higher than in the other groups (p < 0.05). *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001