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Table 3 CpGs differentially methylated at birth and associations with adult cardiovascular traits at 28 years, adjusting for study group, sex and ethnicity

From: DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight

CpG

Nearest Gene

BMI

Systolic BP

LVMI

LVESV

RV basal dia

RAVI

CO

Endo-GLS

LnRHI

cg02001279

ARID3A

        

0.023

cg07835443

SPATA33

 

0.034

       

cg04347477

NCOR2

       

0.016

0.007

cg25975961

KCNH2

0.018

 

†† 0.044*

   

0.041

 

0.042

cg17307655

WHRN

    

0.048

   

0.004

cg06870470

DOCK6

 

0.024

      

0.027

cg09476997

SLC9A3R2

     

0.027††

0.009

††0.040

 

cg12713583

ARID3A

    

0.028

   

0.033

cg00406098

LINC00598

  

0.046

0.032

    

0.032

cg06063190

RNA5SP318

       

†† 0.035*

0.038

cg19333758

RAPGEF3

        

0.005

cg19744173

FBLN7

        

0.019

cg25715278

OAT

        

0.001

cg26708048

DLG4

0.025

0.017

      

 < 0.001

  1. †† Preceding the p value indicates the interaction term of CpG x Study Group is significant p < 0.05; * CpG is significant in VLBW cases when interaction term is also significant in the model