Skip to main content
Fig. 4 | Clinical Epigenetics

Fig. 4

From: Longitudinal DNA methylation profiling of the rectal mucosa identifies cell-specific signatures of disease status, severity and clinical outcomes in ulcerative colitis cell-specific DNA methylation signatures of UC

Fig. 4

DNAm signatures at diagnosis associated with colectomy at 2 years. a Comparison of estimated cell proportions for epithelial, immune cells and fibroblasts obtained from rectal biopsies at diagnosis compared between colectomy and non-colectomy groups. P Values are from the Wilcoxon test. b Cell-specific epigenome-wide DNAm analysis (EWAS) comparing UC patients who underwent colectomy at 2 years (n = 24) to non-colectomy UC patients (n = 175). The blue line represents significant differential methylation at FDR < 0.05, and the red line represents Bonferroni-adjusted genome-wide significance (p < 1e−08)

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us