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Fig. 2 | Clinical Epigenetics

Fig. 2

From: H4-methylation regulators mediated epitranscriptome patterns and tumor microenvironment infiltration characterization in hepatocellular carcinoma

Fig. 2

Three H4M modification patterns and relative biological functions. A A network of correlation including H4M regulators in the meta-data cohorts. B Consensus matrix heatmap defining three H4Mclusters (k = 3) and their correlation areas. C PCA analysis indicated a significant difference in transcriptomes between the three subgroups. D Kaplan–Meier survival analysis for H4Mclusters. E Differences in clinical characteristics and expression levels of H4M regulators between the three distinct H4Mclusters. F Detailed expression landscape of 36 H4M regulators between three H4M modification patterns. *, **, and *** mean p < 0.05, < 0.01, and < 0.001, respectively

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Clinical Epigenetics

ISSN: 1868-7083

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